文章信息/Info

Title:

Cyclotetrasiloxane Fluorescence Probe and Specific Detection Application of Fe3+ Ions

文章編號(hào):

1674-3962(2025)12-1128-07

作者:

周凱麗; 鄧衛(wèi)星; 李曉麗; 黃俊浩; 謝婷婷; 唐艷平

1. 桂林理工大學(xué)材料科學(xué)與工程學(xué)院，廣西 桂林 541000 2. 桂林師范學(xué)院化學(xué)與生命健康學(xué)院，廣西 桂林 541199

Author(s):

ZHOU Kaili;  DENG Weixing;  LI Xiaoli;  HUANG Junhao;  XIE Tingting;  TANG Yanping

1. College of Materials Science and Engineering, Guilin University of Technology, Guilin 541004, China; 2. Department of Chemistry and Pharmacy, Guilin Normal College, Guilin 541199, China

關(guān)鍵詞:

四甲基環(huán)四硅氧烷(D4H); 環(huán)丙沙星; Fe3+檢測(cè); 熒光探針

Keywords:

tetramethylcyclotetrasiloxane(D4H);  cipro-floxacin;  Fe3+ ion detection; fluorescent probe

分類號(hào):

TQ422+.2

DOI:

10.7502/j.issn.1674-3962.202407004

文獻(xiàn)標(biāo)志碼:

A

摘要:

鐵元素是哺乳動(dòng)物體內(nèi)含量最豐富的過(guò)渡金屬，對(duì)維持生命活動(dòng)和健康至關(guān)重要，鐵元素的缺乏和過(guò)量都會(huì)導(dǎo)致嚴(yán)重的疾病，因此鐵離子的檢測(cè)具有重要的意義。通過(guò)硅氫化反應(yīng)制備了環(huán)丙沙星接枝四甲基環(huán)四硅氧烷D4H-HBC，并利用核磁、紫外和熒光光譜儀等對(duì)其化學(xué)結(jié)構(gòu)和光譜特性進(jìn)行了表征。研究表明，D4H-HBC是一種優(yōu)異的Fe3+熒光探針，當(dāng)Fe3+的濃度在5.5×10-5 mol/L以內(nèi)時(shí)能夠線性地測(cè)定其濃度，檢測(cè)極限為0.33 μmol/L，遠(yuǎn)低于美國(guó)國(guó)家環(huán)境保護(hù)局限定的Fe3+安全濃度上限。對(duì)D4H-HBC對(duì)Fe3+的檢測(cè)機(jī)理研究表明，三價(jià)鐵離子以其合適的離子半徑，與D4H-HBC環(huán)上3個(gè)空位的硅氫形成絡(luò)合體，導(dǎo)致D4H-HBC熒光猝滅。環(huán)四硅氧烷熒光探針對(duì)Fe3+有良好的選擇性，并為環(huán)狀熒光探針的設(shè)計(jì)提供了新的思路。

Abstract:

Iron is the most abundant transition metal in mammals, which is essential for maintaining life activities and health, and both deficiency and excess of iron can lead to serious diseases, so the detection of iron ions is of great significance. In this paper, ciprofloxacin grafted tetramethylcyclotetrasiloxane (D4H-HBC) was prepared by hydrosilylation. The chemical structure and optical characteristics were characterized by NMR, UV and fluorescence spectroscopy. D4H-HBC is an excellent Fe3+ fluorescence probe, linearly concentration dependent quenching was observed when the concentration of Fe3+ is less than 5.5×10-5 mol/L, and the detection limit is 0.33 μmol/L, much below the safe concentration limit for Fe3+ ions set by the U-S. Environmental Protection Agency. The quenching mechanism of D4H-HBC is most probably due to the formation of complex between the trivalent iron ions and three silicon hydrogen bonds at three vacancies on the D4H-HBC ring.Cyclotetrasiloxane fluorescent probe has good selectivity for Fe3+ and this work provides a new idea for the design of cyclic fluorescent probe.